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Choosing the best telemedicine software is no longer just a trend, it’s a necessity for modern healthcare. With virtual consultations becoming the standard, clinics, hospitals, and independent practitioners need reliable tools to deliver care remotely while ensuring security and compliance.
The challenge? There are countless options out there. So, which is the best telemedicine software that actually works for you?
In this guide, we examine some of the top telemedicine platforms for 2025, as well as compare their functionalities, price plans, use cases and select the best one for your practice.
To identify the best telemedicine software, we went beyond basic features and evaluated each platform using measurable metrics that matter most to healthcare providers. Here’s what we considered:
By following these metrics, we were able to narrow down to the most trustworthy, secure, and user-friendly telemedicine platforms for the year 2025.
Doxy.me is a simple, web-based telemedicine solution that eliminates the need to download an app, and the overall solution makes virtual visits simple for both patients and providers. The safe for use with patients, secure infrastructure complies with HIPAA while also being user-friendly.
Doxy.me is among the most accessible and cost-effective telemedicine solutions available, mainly for independent practitioners or small clinics. It easily provides one of the most accessible ways for a provider to get going with telehealth due to the free tier and no download options.
Teladoc Health is a telemedicine system designed for remote health care delivery. Teladoc provides the full spectrum of virtual health care from general health to chronic health condition management and mental health. Teladoc is well known for its scalability, serving users at the individual, employer, and health systems, regardless of size and scale, across the world.
Teladoc Health is one of the best telemedicine software solutions overall for enterprises and large healthcare organizations because of its global presence, diversity and depth of services, and remote health management capabilities powered by artificial intelligence.
Amwell is a comprehensive telehealth solution that helps hospitals and health systems deliver on-demand and scheduled virtual care ranging from urgent care to behavioral health while remaining compliant within the industry.
Amwell is one of the trusted names for hospitals because it offers many enterprise-level features, integrations and scalable strategies to deliver telehealth, making it one of the best telemedicine software solutions for large health networks.
The Mend telemedicine platform is focused on improving patient engagement and reducing patient no-shows through automation and predictive analytics. It is a platform designed for practices that are looking to enhance precision, efficiency, and patient outcomes.
Mend is one option that meets the needs of practices that require advanced automation features. The predictive no-show technology it uses helps advance the level of patient attendance dramatically while contributing to practice efficiency.
VSee is a flexible telehealth platform for both solo practitioners and large organizations, with a range of customizable telehealth services available for video visits, remote patient monitoring, and patient triage, among other telemedicine services.
VSee’s flexibility and capacity for supporting more complex telehealth workflows are differentiators from other telehealth platforms. VSee is designed for larger healthcare organizations needing an extensive, customizable telemedicine platform.
Updox is an all-in-one communications platform for healthcare and combines telemedicine with secure messaging, video conferencing, and document sharing. Updox is designed to improve provider interaction with patients.
Updox works great for practices who need more than just video visits. Updox is an entire communication system which connects to your EHR and simplifies patient engagement and administrative workflows.
Healthie is a telehealth and practice management system designed for nutritionists, dietitians, and wellness practitioners. This single platform has video consultations, but it also includes scheduling and charting, as well as billing functionalities.
Healthie is the best telemedicine software for nutrition and wellness providers, offering features that are unique to health professionals while making virtual care effortless.
The telemedicine space is full of widely different credible estimates, different models lead to this disparity, yet generally don’t propose greatly different future forecasted growth. For example, one estimate sees the total global market at $141 billion in 2024, moving to $380 billion by 2030 and with 17-18% CAGRs.
Implication for vendors & buyers: design features should plan for hybrid workflows including using multiple modalities (video + audio + asynchronous), and considering access for older or less skilled tech users.
When selecting telemedicine software, organizations must evaluate whether to develop their own software in-house, or subscribe to a subscription based ready-made software. Both methods have advantages and disadvantages depending on budget, time frame, and business requirements.
When you create your own telemedicine software, you can have full control of all features, data security protocols, and integrations. This is key if you are a health care organization that is seeking to create workflows that are highly customized, specific compliance procedures, or proprietary features of patient engagement. Citrusbug develops telemedicine software to your specifications, with HIPAA compliance, scalability, and integration into existing health care workflows.
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Ready-made solutions (Doxy.me, Teladoc, or Amwell)take less time and are cheaper to get off the ground. They are HIPAA compliant and provide basic telehealth functionality out of the box.
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In today’s digital health ecosystem, selecting the right telemedicine software for your practice is not just a good option—it is an expectation. From increasing patient engagement to facilitating secure and compliant virtual consultations, the right telemedicine software platform with robust telemedicine app features will completely change the way you deliver care.
Whether you are using a ready-made solution like Doxy.me, Teladoc Health, or Amwell, or making the upgrade to a custom telemedicine platform, you will want to validate, at a minimum, scalability, user experience, and security.
If you are making the move to build an in-house telemedicine solution, you will want to partner with an experienced development team. A respected tech partner can help you create a feature rich platform that corresponds with your desired outcomes, while remaining compliant with HIPAA.
Telemedicine isn’t waiting for you to catch up. The question is: will you lead the change—or watch from the sidelines?